Here's the roster breakdown with years of NFL experience in parenthesis after the Bengals announced Tuesday's cuts.
Brandon Allen (5), Joe Burrow (2)
Burrow's second Opening Day start comes 45 years to the day at Riverfront Stadium Ken Anderson's touchdown passes to Chip Myers and Bruce Coslet beat Denver, 17-7, during the 1976 opener in a collaboration of three future NFL offensive coordinators.
WIDE RECEIVERS (7)
Tyler Boyd (6), Mike Thomas (6), Auden Tate (4), Stanley Morgan Jr. (3), Tee Higgins (2), Trenton Irwin (1), Ja'Marr Chase (R)
Just like last year they go with seven receivers. For the first time since 2010, when Chad Johnson and Terrell Owens lined up for the opener in Foxboro, A.J. Green isn't one of them.
RUNNING BACKS (3)
Joe Mixon (5), Samaje Perine (5), Chris Evans (R)
They figure to ease Evans into that third-down role, so Mixon may very well get the chance to start the season showing he's one of the NFL's top backs on all three downs.
TIGHT ENDS (3)
C.J. Uzomah (7), Drew Sample (3), Mitchell Wilcox (1)
They still could be looking here for a No. 3, although they do like the athleticism and speed Wilcox flashed for everyone Sunday with his 21-yard catch on second-and-20 before he left with a concussion.
OFFENSIVE LINE (10)
T Riley Reiff (10), G Xavier Su'a-Filo (8), G Quinton Spain (7), C-G Trey Hopkins (6), T Fred Johnson (3), T Jonah Williams (3), T Isaiah Prince (2), G-T Jackson Carman (R), G-C Trey Hill (R), G-T D'Ante Smith (R)
The re-boot is complete. New line coach Frank Pollack has changed the culture up front with half the players who were not here last year.
DEFENSIVE LINE (10)
NT D.J. Reader (6), E Trey Hendrickson (5), T Larry Ogunjobi (5), T B.J. Hill (4), E Sam Hubbard (4), NT Josh Tupou (4), E Khalid Kareem (2), E Darius Hodge (R), T-E Cam Sample (R), T Tyler Shelvin (R)
They're bigger (Tupou and Shelvin), younger (Hendrickson and Ogunjobi) and better (a healthy Reader and Hubbard).
Jordan Evans (5), Germaine Pratt (3), Markus Bailey (2), Akeem Davis-Gaither (2), Logan Wilson (2)
Wilson becomes the sixth middle backer to start in the last seven Opening Days: Rey Maualuga, Vincent Rey, Kevin Minter, Preston Brown, Josh Bynes.
DEFENSIVE BACKS (10)
SS Ricardo Allen (7), CB Trae Waynes (7), CB Eli Apple (6), SS Vonn Bell (6), CB Chidobe Awuzie (5), CB Mike Hilton (5), SS Brandon Wilson (5), CB Darius Phillips (4), FS Jessie Bates III (3), CB Jalen Davis (2)
With Waynes making the 53, that indicates they'll make him inactive on game day until his hamstring heals. Is that one, two or four weeks? Stay tuned. When Waynes was hurt last season, special teams coordinator Darrin Simmons lost his punt returner when Phillips was elevated. But with the addition of Apple and his 48 career starts, Phillips looks like he can keep returning.
LS Clark Harris (13), P Kevin Huber (13), K Evan McPherson (R)
In the opener, Huber plays his 191st Bengals game, one behind Ken Anderson and third on team's all-time list. Harris plays his 185th game, tying the great Anthony Munoz. McPherson plays in his first, tying him with Marshall Koehn, who hit a PAT in his one game in 2017.
Meet the 2021 Cincinnati Bengals. A look at the roster by numerical order.